Van den Berg replaces Neto Borges, who is ruled out through injury after suffering an ankle problem in Friday’s win at Blackburn Rovers.
Van den Berg came off the bench at Ewood Park, and the Dutchman will partner Jonny Howson at the heart of Boro‘s back four tonight.
Samuel Iling-Junior continues at left-back, with Aidan Morris once again partnering Hayden Hackney at the base of midfield.
Delano Burgzorg and Finn Azaz will fill the wide-attacking positions, with Riley McGree once again on the bench, with Kelechi Iheanacho playing behind central striker Tommy Conway.
MIDDLESBROUGH (4-2-3-1): Travers; Dijksteel, van den Berg, Howson, Iling-Junior; Morris, Hackney; Burgzorg, Iheanacho, Azaz; Conway.
Subs: Glover, Barlaser, Fry, McGree, Whittaker, Forss, Giles, Woolston, McCabe.
LEEDS (4-2-3-1): Darlow; Bogle, Ampadu, Rodon, Firpo; Tanaka, Gruev; James, Aaronson, Solomon; Piroe.
Subs: Meslier, Bamford, Ramazani, Joseph, Guilavogui, Byram, Gnonto, Schmidt, Wober.
