Alderete replaces Jenson Seelt, who is among the substitutes, as is Arthur Masuaku.
The ex-West Ham defender is included in the matchday squad for the first time, replacing Harrison Jones on the bench.
But there’s no place in the squad for Nordi Mukiele, who has trained this week but wasn’t deemed quite ready.
He’s expected to make his debut against Huddersfield Town in the Carabao Cup second round.
Robin Roefs again starts in goal for Sunderland, with Trai Hume, Dan Ballard and Reinildo joining Alderete in the defence.
Granit Xhaka, Noah Sadiki and Habib Diarra again get the nod in midfield, with Chemsdine Talbi and Simon Adingra supporting Eliezer Mayenda.
Enzo Le Fee, Dan Neil, Wilson Isidor, Marc Guiu and Patrick Roberts are all among the substitutes.
Scott Parker has made two changes to his Burnley team, with Jacob Bruun Larsen replacing Oliver Sonne and Lesley Ugochukwu coming in for Josh Laurent.
SUNDERLAND: Roefs, Hume, Ballard, Alderete, Reinildo; Xhaka, Sadiki, Diarra, Talbi, Adingra, Mayenda
SUBS: Patterson, Seelt, Masuaku, Neil, Roberts, Le Fee, Rigg, Guiu, Isidor
BURNLEY: Dubravka, Bruun Larsen, Walker, Ekdal, Esteve, Hartman, Cullen, Ugochukwu, Hannibal, Anthony, Foster
SUBS: Weiß, Worrall, Edwards, Tchaona, Flemming, Ramsey, Sonne, Pires, Laurent
